Multidecadal climate oscillations during the past millennium driven by volcanic forcing
A volcanic source of variation The Atlantic Multidecadal Oscillation (AMO), a 50- to 70-year quasiperiodic variation of climate centered in…
Parallel molecular mechanisms for enzyme temperature adaptation
Some like it hot, others not Enzymes strike a delicate balance between features that enhance chemical reactivity and those that…
Whirls and swirls of polarization
Summary In Greek mythology, sailors feared the perils of getting near the whirlpool said to be created by the sea…
Combined liver-cytokine humanization comes to the rescue of circulating human red blood cells
A red-letter day for RBC research The study of primary human red blood cell (huRBC) disorders such as sickle cell…
Characterization of a common progenitor pool of the epicardium and myocardium
Forming the early heart The heart is the first organ to form during development and is critical for the survival…
Surgical adhesions: A sticky macrophage problem
Summary It is estimated that ∼66% of patients who have gastrointestinal surgery will develop adhesions (1). These bands of scar…
Scaling behavior of stiffness and strength of hierarchical network nanomaterials
A two-stage lightweighting Dealloying allows voids to be created in metals, decreasing the weight of the material. However, when the…
Targeting a neoantigen derived from a common TP53 mutation
Targeted therapies, such as trastuzumab and imatinib, have revolutionized the treatment of cancer patients. All such drugs used thus far…
Eyeless worms detect color
Summary Animals use color vision to explore their environment, recognize mates, avoid predators, and guide feeding decisions. Color vision across…
Redox-active antibiotics enhance phosphorus bioavailability
Phenazines liberate phosphate Bacteria secrete a wide range of small molecules with chemical reactivity that offers multiple functions in different…