Shifting mutational constraints in the SARS-CoV-2 receptor-binding domain during viral evolution
Deep mutational scanning reveals epistatic shifts in the effects of mutations on ACE2 binding, shaping SARS-CoV-2 evolution. ...
‘Zombie papers’ just won’t die. Retracted papers by notorious fraudster still cited years later
Authors who cited flawed work often fail to warn readers, study finds ...
In the Balkans, researchers mobilize to protect a wild river
Plans to dam the upper Neretva River draw concern ...
Comment on “The early origin of a birdlike inner ear and the evolution of dinosaurian movement and vocalization”
Hanson et al. (Research Articles, 7 May 2021, p. 601) claim that the shape of the vestibular apparatus reflects the…
Tumor necrosis factor induces pathogenic mitochondrial ROS in tuberculosis through reverse electron transport
Excess tumor necrosis factor stimulates mitochondria to release pathological reactive oxygen species in tuberculosis. ...
Hidden carbon layer may have sparked ancient bout of global warming
Rift between Greenland and Europe implicated in 56-million-year-old hothouse ...
Small-molecule activation of OGG1 increases oxidative DNA damage repair by gaining a new function
A small-molecule activator of a DNA glycolase enzyme generates a new enzymatic function and increases oxidative DNA damage repair. ...
Nitriles for the production of various amines
Nitriles functionalize amines and ammonia under catalytic hydrogenation conditions ...
Slow and negligible senescence among testudines challenges evolutionary theories of senescence
In the wild, the aging rates of reptiles and amphibians range from negligible to fast depending on protective traits and…